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Although Samuel Chase (a sighner of the Declaration of Independence) began building this house in 1769 while he was a young lawyer, he never resided in it, for he sold it unfinished in 1771 to Edward Lloyd IV, a wealthy Maryland planter and politician. Lloyd immediately engaged architect William Buckland, newly arrived in Annapolis, to continue construction, completed 3 years later with the aid of local architect William Noke.

The structure, one of the first three-story Georgian townhouses erected in the American Colonies, ranks among the finest of its type in the United States and is one of the major attractions in Colonial Annapolis Historic District.

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